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08.30-10.00
Parallel sessions
Session 27
(Doorwerth)
Serotonin systems in psychiatry
(organized under the auspices of
the Dutch-Belgian Society for Experimental and Clinical Neurosciences EKN)
Moderators: Thomas Cremers and
Bart Ellenbroek (Nijmegen)
Mark Millan
(Servier, France): 5-HT and the treatment of depression; a summary of available
concepts/drugs and future perspectives for the novel exploitation of
serotonergic mechanisms (30)
Fokke Bosker
(Groningen): Physiological role of median raphe 5-HT1A autoreceptors
(15)
Herman Westenberg
(Utrecht): Overview of serotonin related clinical developments in treatment of
depression and anxiety (15)
Meg van Bogaert
(Utrecht): The 5-HT1A receptor mouse and anxiety (15)
Edwin Cuppen (Utrecht): Functional characterization of the serotonin transporter knockout
rat (15)
Session 28
(Patio)
Between the ears: neural
mechanisms of sound decoding
Moderators: Gerard
Borst (Rotterdam) and Huib Versnel (Utrecht)
David Moore
(Nottingham, UK): Auditory neuroscience: new frontiers (30)
Adrian
Rodriguez-Contreras
(Rotterdam): A
neuronal microcircuit in the barn owl auditory space map: implications for
coding of binaural cues (15)
John van Opstal
(Nijmegen): Role of the auditory midbrain in sound localization (30)
Nienke van Atteveldt
(Maastricht): Cross-modal modulation of speech sound processing in the planum
temporale (15)
Session 29 (Gelderland)
Molecular aspects
of receptor and channel function
Moderators: Henk
Vijverberg (Utrecht) and Hans van Hooft (Amsterdam)
David Colquhoun
(London, UK): Binding and gating at the single molecule: studies with nicotinic
and glycine receptors (45)
Guus Smit
(Amsterdam): Acetylcholine
binding protein: a structural and functional model of the nicotinic
receptor (15)
Hans van Hooft
(Amsterdam): Structure and function of serotonin 5-HT3 receptors in
the CNS (15)
Chantal Smulders
(Utrecht / Den Haag):
Subunit structure and function of nicotinic ACh receptors (15)
Session 30 (Branding)
Neurogenesis and
gliogenesis in cortical development: molecular and cellular mechanisms
Moderators: Paul Lucassen (Amsterdam) and Erno Vreugdenhil (Leiden)
Stephen
Noctor
(San Francisco, CA, USA):
Patterns of neuronal
migration in the embryonic cortex (30)
Erno Vreugdenhil
(Leiden):
Doublecortin-like, a novel microtubule associated protein
specifically expressed in radial glia and neuronal precursors, is crucial for
mitotic spindle stability (15)
Karin Boekhoorn
(Amsterdam):
Expression of doublecortin and doublecortin-like in the embryonic
nervous system (15)
Sharon Kolk
(Utrecht): ‘Ephective’ signaling:
Eph and ephrins during cortical development (15)
Marco van Ham
(Rotterdam):
Microtubule dynamics and neuronal development (15)
10.00 - 12.00
Poster session
Neuroscience 2 (Branding)
12.00 - 12.45 Session 31
(Branding)
EKN
Keynote Lecture
Chairperson: Bart Ellenbroek
(Nijmegen)
Michel
Ferrari
(Leiden):
Migraine, from patients to transgenic mice models,
..... and back
12.45 - 14.00
Lunch
14.00 - 15.30
Parallel sessions
Session 32
(Branding)
Hormones, plasticity and behavior
Moderators: Paul
Lucassen, Harm Krugers and Marian
Joëls (Amsterdam)
Gal Richter Levin
(Haifa, Israel):
Stress,
cognition and plasticity (30)
Olof
Wiegert
(Amsterdam):
Corticosterone hampers and facilitates synaptic plasticity; the
importance of timing (15)
Danielle
Champagne
(Leiden /
Amsterdam):
Maternal
care and plasticity (15)
Marjolein Gerrits
(Groningen):
Cyclic estradiol treatment modulates the neurobiological
responses to stress (15)
Vera
Brinks
(Leiden):
MR/GR interactions in cognition and emotion (15)
Session 33
(Doorwerth)
How to silence your
nerves: application of small interfering RNA
Moderators: Simone
Niclou (Amsterdam)
and Erno Vreugdenhil (Leiden)
Roderick Beijersbergen
(Amsterdam):
Large
scale RNAi screens in mammalian cells as a tool to identify novel drug targets
(30)
Carlos Fitzsimons
(Leiden): Silencing genes in the living brain: application of small interference
RNA (30)
Erich Ehlert
(Amsterdam): Stimulating axonal
regeneration through siRNA-mediated knock down of semaphorin receptors (15)
Ronald van Kesteren
(Amsterdam):
Possibilities and impossibilities
of dsRNA-mediated knock-down of gene expression in cultured molluscan neurons
(15)
Session 34
(Patio)
Voltage sensitive
dyes as neuronal activity indicators
(Sponsored by Graduate School
Neuroscience Amsterdam ONWA)
Moderator: Wytse
Wadman (Amsterdam)
Jian-Young Wu (Washington, DC,
USA): Propagating waves in neocortical slices: an optical imaging study (45)
Bogden Milojkovic (Rotterdam): Voltage-sensitive dye imaging of
glutamate-evoked dendritic potentials in layer V pyramidal neurons (15)
Tim Heistek (Amsterdam): Voltage sensitive dye imaging of the
mouse prefrontal cortex (15)
Natalie Cappaert (Amsterdam): Stimulated and oscillatory activity
in the hippocampal-entorhinal cortex slice(15)
Session 35 (Gelderland)
The neuromuscular
synapse: basic and clinical aspects
Moderators: Jan
Verschuuren and Jaap Plomp (Leiden)
Clarke Slater
(Newcastle upon Tyne, UK): Current thoughts about the functional organization of
the neuromuscular junction (30)
Bart Jacobs
(Rotterdam): Mechanisms of IVIg therapy in auto-immune neuromuscular disorders (15)
Mariska van der Plas
(Leiden): Novel role of dystrophin at the drosophila neuromuscular junction (15)
Mario Losen
(Maastricht): The role of rapsyn in myasthenia gravis (15)
Ann de Haes
(Groningen): Reversal of competitive neuromuscular block: a revolutionary
approach (15)
15.30 - 16.00
Break
16.00 – 17.00
Session 36 (Branding)
Neurofederation Lecture
Chairperson: Eric
Boddeke (Groningen)
Helmut Kettenmann (Berlin,
Germany):
Mechanisms of neuron-glia interaction
Poster Award
Ceremony Neuroscience 2
17.00 - 18.30
Parallel sessions
Session 37 (Doorwerth)
Mechanism of synaptic
plasticity
Moderators: Nial
Burnashev and Christian Hansel (Rotterdam)
Frances Edwards
(London, UK): LTP - a homeostatic mechanism to wipe the memory slate clean? (30)
Jonathan Jay
Couey
(Amsterdam): Nicotine and the prefrontal cortex synaptic plasticity (15)
Marcel de Jeu
(Rotterdam): Motor learning in LTD/LTP-deficient mice (15)
Wytse Jan Wadman
(Amsterdam): Scaling neuronal excitability in response to non-specific synaptic
activity (15)
Nail Burnashev
(Amsterdam): LTP in mice with prolonged decay kinetics of NMDAR-mediated EPSCs
(15)
Session 38
(Branding)
Neurogenomics: from
molecular anatomy to behavioral phenotype
partially sponsored by EUPEAH
Moderator: Nicole
Datson (Leiden)
Mark Vawter
(Irvine, CA, USA):
Postmortem gene expression studies in neuropsychiatric disorders
(45)
Maarten Morsink
(Leiden):
Generation of a
molecular atlas of the hippocampus using laser microdissection and DNA
microarrays (15)
Yongjun Qin
(Amsterdam): Gene expression changes in single dentate granule neurons after
chronic unpredictable stress (15)
Jonas Hauser
(Zurich, Switzerland):
Long-term
neurobehavioral effects of prenatal dexamethasone in rats and marmosets (15)
Session 39
(Patio)
5-HT and
cognition
Moderator: Arjan Blokland (Maastricht)
Alfredo Meneses
(Mexico City, Mexico): Overview of 5-HT receptor subtypes in learning and memory
(30)
Marleen Wingen
(Maastricht):
Effects of serotonergic drugs on learning and memory in healthy
volunteers (15)
Martijn Meeter
(Amsterdam): Modelling memory functions of 5-HT (30)
Geoffrey van de
Plasse
(Amsterdam): Role of 5-HT in cognitive flexibility in rats (15)
Session 40 (Gelderland)
Living under uncertainty:
towards understanding the foundations of human and animal long-term choice
behavior
Moderator: Ruud van den Bos and
Dennis Schutter (Utrecht)
Edward de Haan (Utrecht):
Overview neuropsychological
processes of decision making in humans in real-life and laboratory models (30)
Dennis Schutter (Utrecht): Psychopathology of decision making in humans
(15)
Henriëtte Prast
(Amsterdam):
Decision making in behavioral finance
(15)
Ruud van den Bos
(Utrecht): Animal models of decision making (15)
Jamilja van der Meulen
(Amsterdam): Neurochemistry of decision making in rats
(15)
19.00
Dinner
21.00-21.45
Session 41
(Branding)
NVP Keynote Lecture
Chairperson: Jaap
Murre (Amsterdam)
Ian Robertson (Dublin, Ireland):
Title pending
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