PROGRAM Wednesday 4 June


(titles are working titles, speaker times including discussion are given between brackets)
08.30 Posters Neuroscience 2 session to be mounted
 
08.30 Parallel sessions 22-25
 
Session 22
 
Transgene across species: neuronal development & plasticity
Moderator: Ineke van der Zee (Nijmegen)
Catharina van der Zee (Nijmegen)
Delayed PNS & CNS axonal outgrowth and behavioural phenotyping in LAR phosphatase-deficient mice (30)
Rob Collin (Nijmegen)
Functional studies on beta-amyloid precursor and related proteins in transgenic Xenopus laevis (15)
Chris Jopling (Utrecht)
Tyrosine phosphorylation in zebrafish development (15)
Rene Wouda (Leiden)
The role of the Drosophila Wnt protein DWnt5 in CNS development (15)
Sander van der Linden (Utrecht)
Novel effectors of G-protein signaling that control behavior in Caenorhabditis elegans (15)

Session 23
Experimental neurophysiology 1: Neuronal networks and synaptic functioning

Moderators: Ype Elgersma and Christian Hansel (Rotterdam)
Jeffrey Magee (New Orleans, LA, USA)
Regulation of local dendritic spike initiation and propagation in CA1 pyramidal neurons (45)
John Weber (Rotterdam)
Climbing fiber-evoked calcium signals and plasticity in cerebellar Purkinje cells (15)
Volker Mack (Amsterdam)
Conditional expression of GluR-A-dependent synaptic plasticity in hippocampal connections (15)
Ype Elgersma (Rotterdam)
Genetic enhancement of learning by modulating transmitter release (15)
 
Session 24
Molecular mechanisms of neurite growth-inhibitory factors
Moderator: Simone Niclou (Amsterdam)
Christine Bandtlow (Innsbruck, Austria)
Axonal regeneration in the CNS: role of the inhibitory molecules Nogo and MAG and their receptors (45)
Mariette Driessens (Utrecht)
Signalling of the plexin-B1 semaphorin receptor to Rho GTPases (15)
Joris de Wit (Amsterdam)
Secreted semaphorins in the adult nervous system: subcellular localization of epitope-tagged sema3A (15)
Francis van Horck (Amsterdam)
The role of type I phosphatidylinositol 4 phosphate 5 kinase (PIP kinase) in neurite remodeling (15)

Session 25
Blood-brain-barrier

Moderators: Monique Mulder (Maastricht) and Bert de Boer (Leiden)
Rachid Deane (New York, NY, USA)
Key role of the blood-brain barrier in the pathogenesis of Alzheimer's disease (30)
Bert de Boer (Leiden)
The neurovasculature as a targeting organ (15)
Wouter Veldhuis (Utrecht)
Interferon-beta attenuates inflammation after acute ischemic stroke (15)
Paulien Ravenstijn (Leiden)
Development and use of a new model for Parkinson's disease to ultimately study the relation between disease progression, blood-brain barrier functionality and effects of antiparkinsonian drugs (15)
Paula Jansen (Maastricht)
Apolipoprotein E is necessary for the maintenance of the blood-brain barrier integrity during aging; implications for Alzheimer's disease? (15)
 
10.00 POSTER SESSION NEUROSCIENCE 2 (including break)
  
11.30 Session 26
hersenstichting lecture
Chairperson: Pim French (Rotterdam)
Tim Bliss (London, UK)
LTP story
       
12.15 Lunch
 
13.30 Parallel sessions 27-30
 
Session 27
Experimental neurophysiology 2
Moderators: Huib Mansvelder and Arjen Brussaard (Amsterdam)
Olga Garaschuk (Munich, Germany)
In vivo imaging of neuronal networks (30)
Gerard Borst (Rotterdam)
Vesicle dynamics in a large brainstem terminal (15)
Huib Mansvelder (Amsterdam)
Two-photon imaging of cholinergic modulation of PFC networks (15)
Laurens Bosman (Munich, Germany)
BDNF-induced longterm plasticity in climbing fiber-Purkinje cell synapses (15)
Christiaan de Kock (Amsterdam)
Somatic release induced by NMDA receptor activation in CNS neurons (15)

Session 28
Molecular mechanisms of learning and memory
Moderator: Pim French (Rotterdam)
Dietmar Kuhl
(Berlin, Germany)
Learning about activity-dependent genes (30)
Pim French (Rotterdam)
LTP-associated gene expression (15)
Matthijs Verhage (Amsterdam)
Presynaptic plasticity and memory (30)
Renate Hukema (Rotterdam)
Genetic analysis of salt adaptation in the nematode C. elegans (15)

Session 29
Neurogenomics
Moderators: Erno Vreugdenhil (Leiden) and Guus Smit (Amsterdam)
Cor Verweij
(Amsterdam)
A genomic view of complex diseases (30)
Gerard Martens (Nijmegen)
A natural knock-down of a gamma-secretase component in a rat model for stress-induced psychopathology (15)
Dorine Schmidt-Feldker
(Leiden)
Towards the molecular basis of individual differences in vulnerability to stress (15)
Floor Stam (Amsterdam)
Genomic response of the dorsal root ganglion after sciatic nerve injury (15)
Kawan Li (Amsterdam)
Proteomics analysis of the postsynaptic density (15)
 
Session 30 
 
Spinal cord lesions: new therapies
Moderator: Frank Hamers (Utrecht)
Michele Basso (Columbus, OH, USA)
Recovery of function after spinal cord injury: from bench to bedside (45)
Tanja Effing (Utrecht)
The functional effects of treadmill training in three persons with chronic incomplete spinal cord injury (15)
Guido Koopmans (Maastricht)
Effects of enriched housing on neuroplasticity in the CPG region (15)
Susanne Hermanns (Düsseldorf, Germany)
Suppression of fibrous scarring in a rat model of spinal cord injury leads to functional regeneration
  
15.00 Break
15.30 Session 31
EKN lecture
(Dutch-Belgian Society for Experimental and Clinical Neuroscience)
Chairperson: Erno Vreugdenhil (Leiden)
Gert-Jan van Ommen (Leiden)
From genome to function
 
including Poster award ceremony NEUROSCIENCES 2

  
16.30 Parallel sessions 32-35

Session 32
Experimental neurophysiology 3
Moderators: Maarten Kamermans and Wytse Wadman (Amsterdam)
Thomas Euler
(Tübingen, Germany)
Directional-selective calcium signals in dendrites of retinal starburst cells (30)
Marjelle van Leeuwen (Amsterdam)
The retinal mechanism of color constancy (15)
Matthew Larkum (Heidelberg, Germany)
Signalling of layer 1 and whisker-evoked Ca2+ and Na+ action potentials in distal and terminal dendrites of rat neocortical pyramidal neurons in vitro and in vivo (30)
Michiel Remme (Amsterdam)
Gain normalization in hippocampal networks with feedback and feedforward inhibition (15)

Session 33
Schizophrenia
Moderator: Jeffrey Glennon (Weesp)
Gavin Reynolds
(Sheffield, UK)
Amino acid dysfunction in schizophrenia (30)
Jeffrey Glennon (Weesp)
Disrupted mediodorsal thalamic-prefrontal cortical transmission in schizophrenia? Carlsson's hypothesis revisited (15)
Billy O'Connor (Dublin, Ireland)
Evidence for a role of the prefrontal cortical GABA-B receptor in the neurobiology of schizophrenia (15)
Annelies Olijslagers (Amsterdam)
The role of 5-HT2a/c receptors in regulating the firing rate of A9 and A10 dopaminergic cell bodies (15)
Samantha Smith (Sheffield, UK)
The role of cannabinoids in regulating glutamate and GABA release from the prefrontal cortex (15)

Session 34
Spinal cord and treatment of pain
Moderators: Maarten van Kleef and Bert Joosten (Maastricht) 
Marshall Devor
(Jerusalem, Israel)
Sensory neurons ring out pain (30)
Jan van Zundert (Diepenbeek, Belgium)
Pulsed radiofrequency treatment adjacent to the cervical dorsal root ganglion: effects on c-fos expression (15)
Eline Pragt (Maastricht)
Models for CRPS-I (15)
Dorien Vrinten (Utrecht)
Assessment of mechanical allodynia: a comparison of 'Catwalk' and von Frey measurements (15)
Kris Vissers (Beerse, Belgium)
Neuro-immunological changes in neuropathic pain and stress (15)
 
Session 35
Tryptophan, serotonin and cognition

Moderator: Jeroen Schmitt (Maastricht)
Wim Riedel (Cambridge, UK)
Tryptophan, mood and cognition (30)
Cindy Lieben (Maastricht)
Challenging the cognitive effects of acute tryptophan depletion in the rat (15)
Lisbeth Evers (Maastricht)
The effects of tryptophan depletion on cognitive flexibility in healthy volunteers (15)
Sascha Russo (Groningen)
Neuropsychological investigation into the carcinoid syndrome (15)
Linda Booy (Leiden)
The effects of rapid depletion of tryptophan on cognitive functions in depressive patients: dose-response relationship? (15) 
 
19.00 Dinner
 
21.15 Session 36
ELSEVIER lecture
chairperson: Peter Hagoort (Nijmegen)
Christian Keijsers (Parma, Italy)
From mirror neurons to actio understanding