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| (titles are working titles, speaker times including discussion are given between brackets) |
| 08.30 | Posters Neuroscience
1 session to be mounted |
| 08.30 |
Session 10 NVE teaching session on Experiments of nature Chairperson: Hans Romijn (Leiden) Marcel Karperien (Leiden) Small and mentally retarded: in search for the gene defect (30) Jan Mol (Bethesda, MD, USA) Between mouse and man; the dog as a spontaneous model for mammary and prostate cancer (30) Sadaf Farooqi (Cambridge, UK) Lessons from monogenetic obesity syndromes (30) |
| 10.00 | Break |
| 10.30 |
Parallel sessions 11-14 Session 11 Hormones and the brain: implications for aging and cognition Moderators: Sytze van Dam and Hans Koppeschaar (Utrecht) William Sonntag (Durham, NC, USA) Growth hormone / IGF-1 and the genesis of brain aging (30) Lucia Arwert (Amsterdam) Brain imaging, the somatotropic axis and cognition in aging people (15) Marijn Lijffijt (Utrecht) Cognitive function and CNS physiology in growth hormone deficiency (15) Sanne Manschot (Utrecht) Hyperglycemia and cognitive function: a model for accelerated aging? (15) Eva Hogervorst (Oxford, UK) Role of testosterone in cognitive decline in the elderly (15) Session 12 Central regulation of peripheral energy metabolism Moderators: Michaela Diamant (Amsterdam) and Hanno Pijl (Leiden) Silvana Obici (New York, NY, USA) The role of central insulin signaling in peripheral energy metabolism (30) Margriet Ouwens (Leiden) Insulin signaling in the brain (15) Felix Kreier (Amsterdam) The role of the autonomic nervous system in energy metabolism (15) Celine Morens (Groningen) Central regulation of protein metabolism (15) Anita van der Hoek (Leiden) Central effects of NPY on glucose and lipid metabolism (15) Session 13 Stress hormones, anti-glucocorticoids and brain function Moderators: Ron de Kloet and Erno Vreugdenhil (Leiden) Ted Dinan (Cork, Ireland) Hypothalamic-pituitary-adrenal axis dysfunction in depression: causation and physical consequences (30) Martin Verkuyl (Amsterdam) Corticosteroids regulate neuronal control of HPA-axis at the level of the PVN (15) Alexa Veenema (Groningen) Differences in basal and stress-induced changes HPA regulation of wild house mice selected for high and low aggression (15) Ron de Kloet (Leiden) Antiglucocorticoids: putative action mechanism as anti-depressant (30) Session 14 ChildHOOD epilepsy Moderator: Onno van Nieuwenhuizen (Utrecht) Ineke Bos (Utrecht) Early markers of epileptogenesis in blood (15) Floor Jansen (Utrecht) Diffusion weighted imaging in tuberous sclerosis (15) Robbert Notenboom (Utrecht) Altered expression of mGluR1 in an animal model of febrile seizures (15) Mark Nellist (Rotterdam) Constitutional and somatic mutations in tuberous sclerosis complex (15) Martin Staudt (Tübingen, Germany) Brain plasticity after early lesions in the child (30) |
| 12.00 | Lunch |
| 13.30 | Parallel
sessions 15-17 Session 15 Neural regulation of body weight Moderator: Roger Adan (Utrecht) Lora Heisler (Boston, MA, USA) Central serotonergic and melanocortin pathways regulating food intake and body weight (30) Anneke Alkemade (Amsterdam) Thyroid hormone, the human hypothalamus and illness (15) Jacquelien Hillebrand (Utrecht) Increased melanocortin system activation in activity-based anorexia (15) Koert de Vries (Groningen) Differential effects of long-term central melanocortin or leptin administration on metabolism and body weight (15) Martien Kas (Utrecht) Brain region specific forms of obesity (15) Session 16 Trophic actions of estrogens: implications for cognition, mood and neuroprotection Moderators: Katalin Horvath and Paul Luiten (Groningen) Christian Behl (Mainz, Germany) Hormones for the brain: protection against neurodegeneration (30) Paula Jansen (Maastricht) Estrogens affect learning and memory processes in apolipoprotein E-knockout mice (15) Katalin Horvath (Groningen) Trophic actions of estrogens and the cholinergic system (15) Marjolein Gerrits (Groningen) Female stress vulnerability: the role of estrogens in chronic stress reactivity (15) Guillen Fernandez (Nijmegen) Hormone and region specific changes in cortical representations of language during the menstrual cycle: an fMRI study (15) Session 17 Neuromodeling: an approach to the study of epileptogenesis Moderators: Tineke van Rijn (Nijmegen) and Pauly Ossenblok (Heeze) Klaus Lehnertz (Bonn, Germany) What can be expected from mathematic models for epileptic phenomena: with in mind the epileptogenesis and consequently the anticipation of, detection of and interference with epileptic seizures (30) Fabrice Wendling (Rennes, France) Mathematic models for convulsive epileptic phenomena (30) Piotr Suffczynski (Heemstede) Mathematic models for non-convulsive epileptic phenomena (15) Michael van Putten (Den Haag) Functional link rates in the human brain and detection of seizures (15) |
| 15.00 |
POSTER SESSION NEUROSCIENCE 1 (including
break) |
| 16.30 | Parallel
sessions 18-20 Session 18 Markers of neurodegenerative diseases Moderator: Marcel Verbeek (Nijmegen) Magnus Sjögren (Göteborg, Sweden) Cerebrospinal biomarkers in the diagnosis of dementia disorders (30) Niki Schoonenboom (Amsterdam) Differentiation of early onset Alzheimer's disease from frontotemporal lobar degeneration by cerebrospinal fluid phospho-tau-181 and amyloid b42 (15) Wilson Abdo (Nijmegen) Cerebrospinal fluid analysis differentiates Multiple System Atrophy from Parkinson’s disease (15) Bart van de Warrenburg (Nijmegen) Cerebrospinal fluid autoantibodies in patients with cerebellar ataxia (15) Evelien Lemstra (Amsterdam) Cerebrospinal fluid 14-3-3 proteins in diagnosing Creutzfeldt-Jakob disease (15) Session 19 Early life events Moderators: Harm Krugers and Marian Joëls (Amsterdam) Michael Meany (Montreal, Canada) Maternal care, gene expression and the development of individual differences in behavioural and endocrine responses to stress (45) Patrick Kamphuis (Wageningen) Longterm effects of synthetic steroids on synaptic plasticity (15) Mathias Schmidt (Leiden) Neuroendocrine and molecular consequences of maternal deprivation in wild type and CRH receptor 1-deficient mice (15) Bernette Elzinga (Leiden) Late consequences of early traumatic experience in humans (15) Session 20 Gene therapeutic approaches in neurodegenerative diseases Moderator: Gerard Boer (Amsterdam) Frits Fallaux (Amsterdam) Developments in viral vector-mediated gene therapy (15) Anne-Marie van Dam (Amsterdam) Towards viral-vector mediated gene transfer in experimental Multiple Sclerosis (15) Veerakumar Balasubramaniyan (Groningen) Bone marrow stem cells as a source for cell transplantation in MS (15) Liselijn Wisman (Utrecht) In vivo gene therapy in an in vivo ALS model (15) William Hendriks (Amsterdam) Towards gene and cell therapy in ventral root avulsion (15) Ronald Verwer (Amsterdam) Basic studies on human postmortem tissue slices exploring gene therapeutic approaches in AD (15) |
| 19.00 | Dinner including Poster Award Ceremony Neurosciences 1 |
| 21.15 |
Session 21 NEUROFEDERATIE LECTURE Chairperson: Gerard Boer (Amsterdam) Patrick Aebischer (Lausanne, Switzerland) GDNF (gene) therapy and PD |