PROGRAM Monday 2 June

Session 1
ENDOCRINOLOGY KEYNOTE LECTURES
Chairperson: Marjanne Everts (Utrecht)
Peter Trainer (Manchester, UK)
(sponsored by Pharmacia, Woerden, NL)
Metabolic effects of GH antagonism in patients with acromegaly (30)
Theo Visser (Rotterdam)
Genetics of thyroid function (30)
 

Parallel sessions 2-4
 
Session 2
Thyroid and the heart
Moderators: Marjanne Everts (Utrecht) and Warner Simonides (Amsterdam)
Warner Simonides (Amsterdam)
Role of thyroid hormone in heart failure (30)
Ivaylo Stoykov (Amsterdam)
Zonal distribution of thyroid hormone receptor isoforms in heart (15)
Edith Friesema (Rotterdam)
The role of monocarboxylate transporter 8 in tissue-specific uptake of thyroid hormone (15)
Sabine van der Heide (Utrecht)
Effect of hypo- and hyperthyroidism on UDP-glucuronyltransferase-, ß-glucuronidase- and deiodinase type I and II activity in homogenates of different organs from adult rats (15)
Mieke van Beeren (Amsterdam)
Dronedarone: a thyroid hormone receptor alpha 1 selective antagonist (15)  

Session 3
Nuclear hormone receptors as lipid sensors
Moderator: Sander Kersten (Wageningen)
Pascal Ferré (Paris, France)
The role of SREBP-1 in the regulation of hepatic lipid and glucose metabolism (30)
Aldo Grefhorst (Groningen)
The role of liver X receptors in control of hepatic fat and carbohydrate metabolism (15)
Robert Kleeman (Leiden)
New insights into the anti-inflammatory action of PPARalpha (15)
Stephane Mandard (Wageningen)
Characterization of PPARalpha target genes (15)
Tineke Kok (Groningen)
Effects of FXR-deficiency on bile salt and cholesterol metabolism (15) 

Session 4
GnRH and GnRH receptors in human and non-human species
Moderator: Cornelis Lambalk (Amsterdam)
Sietse Mosselman (Oss)
Outline of the issue (15)
Jimmy Neill (Birmingham, AL, USA)
GnRH and GnRH receptor genes in the human genome (30)
Jan Bogerd (Utrecht)
Differences in structure-function relations between nonmammalian and mammalian gonadotropin-releasing hormone receptors (15)
Judith Huirne (Amsterdam)
FSH hormone release: a role for GnRH II? (15)
Jurgen Piek (Amsterdam)
GnRH and its receptors in human female reproductive organs (15) 

SATELLITE BIORHYTHMS (part 1)
  

Session 6
Adult consequences of childhood endocrine disorders
Chairperson: Jan Maarten Wit (Leiden)
Gianni Bocca (Amsterdam)
Transitional care of pituitary disease, the paediatrician's perspective (15)
Saskia ten Have (Rotterdam)
Transitional care of pituitary disease, the adult endocrinologist’s perspective (15)
Nike Stikkelbroeck (Nijmegen)
Transitional care of congenital adrenal hyperplasia, the paediatrician's and adult endocrinologist’s perspective (30)
Annemieke Boot (Rotterdam)
Protecting the teenage skeleton against future osteoporosis (30)

Session 7
Local regulation of hormone bioactivity in target cells
Moderator: Theo Visser (Rotterdam)
Brian Walker (Edinburgh, UK)
Regulation of corticosteroid bioactivity by 11beta-hydroxysteroid dehydrogenase (30)
George Kuiper (Rotterdam)
Regulation of thyroid hormone bioactivity by deiodination (15)
Hans van Leeuwen (Rotterdam)
Regulation of vitamin D3 bioactivity by hydroxylation (15)
Pim de Ronde (Rotterdam)
Testosterone: androgen and estrogen (15)
Joop Janssen (Rotterdam)
Regulation of IGF-1 bioactivity by IGF-1 binding proteins (15) 

Session 8
Neuroendocrinology of gut peptides
Moderators: Tanja Adam (Maastricht) and Anton Scheurink (Groningen)
Thomas Lutz (Zürich, Switzerland)
Gastrointestinal and pancreatic hormones in the regulation of energy balance (30)
Tanja Adam (Maastricht)
Long term effect of physical activity induced weight loss on GLP-1 release in overweight subjects (15)
Cor van der Leest (Rotterdam)
Ghrelin as a new tumor marker for neuroendocrine tumors (15)
Esther van der Wall (Groningen)
Peripheral CCK and the mediation of satiety (15)
Peter Wielinga (Groningen)
Factors mediating glucose uptake from the gastrointestinal tract (15)

SATELLITE BIORHYTHMS (part 3)